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pentobarbital will lessen the level or result of larotrectinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will minimize the extent or influence of norgestrel by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Carefully. Average CYP3A4 inducers may lessen progestin focus; take into account us